Using antibody tests Right Now means no sound. But that could soon change

Using antibody tests Right Now means no sound. But that could soon change

In the largest study to date, researchers found looking human antibodies that have recovered from COVID-19, some surprises that can also be a person, but also affect not only how useful antibody-based treatments, the results, test antibody could what it really means. Right now, get most of the people who have antibody tests to find out if they are infected with COVID-19 or not, how many experience mild or no symptoms of the disease. But this information could be used in theory to answer questions far beyond personal curiosity. public health experts, these results are important to get an idea of ​​how deep COVID-19 specific communities penetrated and as it was and the widespread infection, such as Wild maybe could be again. to take the test more people, the more accurate these prevalence data can be. But there are other equally important ways that antibody test may help monitor and control ultimately the pandemic in the coming months. Posted publish a preprint server for studies in the study medRxiv before the inspection, one team analyzed at the Lindsley F. Kimball Research Institute of the New York Blood Center and Rockefeller University donated 370 plasma samples from people of COVID -19 recovered and she found some surprising results. The researchers used different testing methods of antibodies, including two commercially available tests for antibodies document levels of the immune system in patients who are against SARS-CoV-2, the virus behind COVID-19 (Edited by similar measure reliable. Everything) the researchers then tested these antibodies against SARS-CoV-2 of virus in laboratories reserves to see if the antibodies actually how could neutralize the virus (Doubles that mimic actual virus, no infection is search settings laboratory are often used to prevent the spread of diseases). In total, approximately 88% of the people has reached levels of antibodies against the virus to change. But only 10% of them a great deal had been able to neutralize the lab-based version of COVID-19 virus and on the opposite side of the spectrum, 17% has been answered almost free of antibodies to their infection. What this means is, the so-called SARS-CoV-2 idea can be complicated “natural immunity” more than that, says that anyone with COVID-19 infected sharply protected by the remains of Dr. Larry Luchsinger disease, alternate member of the Research Institute and lead author of the study. “There was a large group of people who had essentially no activity neutralize [the virus]. What we found was that surprising that in all tests, there was a large variation in the results or antibody that people have to learn. “it should be collected to understand even more data, the patients healed why so wide spectrum of levels of antibodies, and how people could affect the capacity of infection with the virus for the future combat. The average results, for example, that there may be several ways to combat the SARS-CoV-2 infection. Since all men recovered from their infections, the immune system of some people can greatly antibody-based, while others are aimed at different types of cells fight the virus. The results make a strong case for doctors not only testing for antibody levels, but to learn what these values ​​might mean to fight for every patient the possibility of further infection. to do this type of provision is not yet possible, but it could be on the levels of patients treated with other data antibodies. “At that moment, little antibody and its benefits are well known,” Michael Mina, assistant professor of epidemiology and professor at the Center for Infectious Disease Dynamics at Harvard T.H. Chan School of Public Health, said in a question and answer session with reporters. How to become available more data, you may be able to determine the doctors what level the infected antibodies are more likely to protect against SARS-CoV-2 back and share this information with their patients, which would then know how vulnerable they they can be re-infection. Luchsinger The results are a start to build those data; The study includes detailed results on the levels of two commercial antibody tests, one of the garden and the other from Abbott, and the results in how well these antibodies identified in tests might neutralize the virus in a test environment. But: “The unfortunate thing is, the only way [sure] to know what level is required neutralizing activity to take people and put them back COVID-19,” says Luchsinger. “There are ethical dilemmas in order to do such a thing.” However, the antibody test to use, able to identify people who have little ability to neutralize the virus, and those who are better able to do so, in advising them on how to stop the spread of COVID-19 might be important. “To have people who do not do much neutralizing effect should be careful and take precautions to keep them and their loved ones safe,” says Luchsinger. To get a more complete picture of the antibody responses to COVID-19 are actually agents for immunity, Luchsinger extends levels of study and human antibodies with their symptoms stay on to see if there was a correlation between how human symptoms serious, and how active their antibodies could neutralize the virus. This information will be even more important in the coming months, as employers and public health officials rely on this information to keep track of how people in the community can feel safe when they are at work, or on public transport or public meetings. antibody test is also important because vaccines are rolled out, such as public health officials will probably vaccination people with low or no antibody levels want to get, the more prone to infection. The pursuit of these antibody levels over time among vaccinated are also experts of useful information about how the vaccines work well. “We just need a little ‘patience and let the tests,” says Mina. “But the infrastructure for the testing requirements of antibodies are also now, when properly set, that we do not immediately benefit [to find people who have been infected], in addition to seeing.”
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